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SEAJMS|ISSN: 2520-7342
Case ReportPeer-reviewedOpen Access · CC BY-NC-SA 4.0

Colchicine-induced pancreatitis in an elderly patient with renal impairment: A case report

Shakil Ahmed Chohan1, Diraviyam Balasubramanian2, Thet Thet Soe3

  1. 1 Changi General Hospital (corresponding author)
  2. 2 Changi General Hospital, Singapore
  3. 3 Changi General Hospital

DOI: 10.5281/zenodo.3723458 · Published 2019-12-30 · pp. 5-6

Abstract

Colchicine is widely used in the treatment of acute gout. It has a narrow therapeutic window and can be extremely toxic in vulnerable older patients especially those with renal impairment. The most common side effects are gastrointestinal related, such as nausea, vomiting, diarrhea and abdominal pain. Colchicine-induced acute pancreatitis is very rare especially within therapeutic dose range. We report an atypical presentation of acute pancreatitis caused by a therapeutic dose of colchicine in an elderly patient with preexisting chronic renal disease.

Keywords: acute pancreatitis, atypical presentation, older person, colchicine-induced, renal impairment